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EFFECT OF FLUORIDE CONCENTRATION ON REMINERALIZATION OF ARTIFICIAL CARIOUS ENAMEL

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Abstract

°á·Ð
ºÒ¼ÒÀû¿ë¿¡ µû¸¥ Żȸ¹ý¶ûÁúÀÇ À缮ȸȭȿ°ú¸¦ Æò°¡Çϱâ À§ÇÏ¿©, ÇÑ¿ì ÁßÀýÄ¡ÀÇ ¹ý¶ûÁú¸é
¿¡ Àΰø¿ì½Äº´¼Ò¸¦ Çü¼ºÇÏ°í, ºÒ¼Ò ¹Ì󸮱º ¹× 100, 5,000 ±×¸®°í 12,000ppm APF¿ë¾×À» ¿ì
½ÄÇü¼º ¹ý¶ûÁú¸é¿¡ Àû¿ëÇÑ ºÒ¼Ò 󸮱ºÀ¸·Î ºÐ·ùÇÏ¿´À¸¸ç, Á¤»ó¹ý¶ûÁú¸éÀ» ´ëÁ¶±ºÀ¸·Î ÀÌ¿ë
ÇÏ¿´´Ù. º» ¿¬±¸¿¡¼­´Â ÁÖ»çÀüÀÚÇö¹Ì°æ(SEM), È­Çкм®¹ý, ±×¸®°í EPMA¸¦ »ç¿ëÇÏ¿© ºÒ¼Ò
³óµµ Â÷ÀÌ°¡ ¹ÌÄ¡´Â ¹ý¶ûÁúÇ¥¸éÀÇ ¹Ì¼¼±¸Á¶ÀÇ º¯È­ ¹× ¹ÝÀÀÈ­ÇÕ¹°ÀÇ ¿ø¼ÒºÐ¼®°ú ÇÔ²² ¹ý¶û
Áú³»ºÎÀÇ ±íÀÌ¿¡ µû¸¥ Ä®½·, ÀÎ ±×¸®°í ºÒ¼ÒÀÇ Á¤¼º ¹× Á¤·®ºÐ¼®À» ½ÃÇàÇÑ °á°ú, ´ÙÀ½°ú °°
Àº °á·ÐÀ» ¾ò¾ú´Ù.
1. 100ppm APF¸¦ Àû¿ëÇÑ ¹ý¶ûÁú¸éÀº ´õ¿í ŻȸµÊÀ¸·Î¼­ Çü¼ºµÈ Å« ±¸¸í(hole)°ú ±Õ¿­µÈ
ÇÔ¸ôºÎ¿¡ ¼Ò¼ö °ú¸³ÀÚ°¡ ´À½¼ÇÏ°Ô ºÎÂøµÇ¾úÀ¸¸ç, 5,000ppm APF Àû¿ë¸é¿¡¼­´Â 0.5¡­l¥ìm Å©
±â¸¦ °®´Â ¼ö ¸¹Àº ±¸ÇüÀÇ °ú¸³ÀÚ ÇüÅÂÀÇ Ä§Àü¹°ÀÌ, 12,000ppm APFÀû¿ë½Ã´Â ÇÑÃæ °ß°íÇØÁø
¹ý¶ûÁú Ç¥¸éÀ§¿¡ ´Ù¾çÇÑ Å©±â·Î¼­ ±ä¹ÐÇÏ°Ô Ä§ÀüµÈ Àå¹æÇü ¹× ÀÔ¹æÇüÀÇ ºÒ¼ÒÈ­ÇÕ¹°ÃæÀÌ °¢
°¢ °üÂûµÇ¾ú´Ù.
2. KOH¿ë¾×¿¡ ÀÇÇØ À¯¸®µÈ ºÒ¼Ò·®Àº °í³óµµÀÇ ºÒ¼Ò°¡ Àû¿ëµÈ ½ÇÇ豺ÀÏ ¼ö·Ï Áõ°¡µÈ °á
°ú¸¦ ³ªÅ¸³ÂÀ¸¸ç, ¥²±º¿¡ ºñÇØ ¥³±º ¹× ¥´°£¿¡ Åë°èÀû À¯ÀÇÇÑ Â÷ÀÌ°¡ Á¸ÀçÇÏ¿´´Ù(p<0.05).
3. EPMA°á°ú, 5,000ppm°ú 12,000ppm APP¸¦ Àû¿ëÇÑ ¹ý¶ûÁúÀÇ ÃÖÇ¥¸éºÎÅÍ 30¥ìm À̳»ÀÇ
±íÀÌ¿¡¼­ Ä®½·°ú ÇÔ²² ºÒ¼ÒÀÇ ÇöÀúÇÑ Áõ°¡¾ç»óÀÌ ³ªÅ¸³µÀ¸³ª, 100ppm APF°¡ Àû¿ëµÈ ¹ý¶û
Áú¿¡¼­´Â ¸ðµç ±íÀÌ¿¡¼­ Á¤»ó ¶Ç´Â Żȸ¹ý¶ûÁú¿¡ ºñÇØ ºÒ¼Ò¼ººÐ¸¸ÀÌ ´Ù¼Ò Áõ°¡µÈ ¾ç»óÀ» º¸
¿´´Ù.
4. ¥³±º°ú V±ºÀÇ °æ¿ì ¹ý¶ûÁúÀÇ 5¿Í 15¥ìm ±íÀÌ¿¡¼­ ¥°±º, ¥±±º ±×¸®°í ¥²±ºº¸´Ù ³ôÀº
Ä®½·/ÀÎ ¹«°Ôºñ¸¦ ³ªÅ¸³ÂÀ¸¸ç, ºÒ¼Ò³óµµµµ ¸ðµç ±íÀÌ¿¡¼­ ¥°±º, ¥±±º ±×¸®°í ¥²±º¿¡ ºñÇØ À¯
ÀÇÇÑ Â÷À̸¦ ³ªÅ¸³Â´Ù(p<0.05).
#ÃÊ·Ï#
The purpose of this study was to evaluate the remineralized effect of fluoride on
artificial carious enamel after topical fluoride application and to certificate the most
appropriate fluoride concentration.
Artificial demineralized bovine enamel blocks were randomly assigned to four groups,
and placed in no fluoride, 100, 5,000 and 12,000ppm acidulated phosphate fluoride
solution. Sound enamel blocks without artificial carious lesion were used as control
group.
In this study, the morphological characteristics of treated enamel surface and effect of
fluoride concentration on remineralization of artificial carious enamel has been
investigated by using scanning electron microscopy, chemical analysis and electron probe
microanalysis compared with the effect of various fluoride concentration.
The Following results were obtained.
1. The enamel surface treated with 100ppm APF was observed more demineralized
surface with lots of holes and loosely bounded a few globules. 5,000ppm APF treatment
produced a deposits of numerous spherical globules 0.5¡­1¥ìm in diameter and distinctive
rectangular and cuboidal shaped deposits were formed by 12,000ppm APF treatment.
2. Amount of KOH-soluble fluoride on enamel surfaces was increased according to
treated fluoride concentration level. In the ¥³ and ¥´ group were showed significantly
higher than that in the ¥² group(p<0.05).
3. After treatment with 5,000 and 12,000ppm APF, a remarkable elevation of the
fluoride profile was observed within 30¥ìm of the outermost layer and was accompanied
simultaneously by a high elevation of the calcium profile. However, specimens treated
with 100ppm APF showed only a small elevation of fluoride within whole depth than
that in the sound and demineralized enamel specimens.
4. In the ¥³ and ¥´ group, Ca/P weight percent ratio were showed higher than that in
the ¥°, ¥±, ¥² group in 5 and 15¥ìm depth, and fluoride content were showed
statistically different than that in the ¥°, ¥±, ¥² group in all depth(p<0.05).

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